Method of expressing gene in transgenic birds using retrovirus vector and transgenic birds thus obtained

Abstract

The present invention has for its object to provide a G0 transgenic chimera bird which is introduced an antibody gene with a replication-defective retrovirus vector, and produces an antibody by expressing the transgene; a production method of an antibody which comprises recovering the antibody expressed by the produced G0 transgenic chimera bird; and a production method of a G0 transgenic chimera bird which comprises incubating a bird fertile egg, and injecting an embryo after and exclusive of a period immediately after the start of incubation with a retrovirus vector. That is, the present invention relates to a G0 transgenic chimera bird which is introduced an antibody gene with a replication-defective retrovirus vector, and produces an antibody by expressing a transgene.

Dependencies are inferred from the claim text.