Self-expanding device for the gastrointestinal or urogenital area
AssigneeMnemoscience GmbH
InventorsAndreas Lendlein, Robert Langer
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AssigneeMnemoscience GmbH
InventorsAndreas Lendlein, Robert Langer
Estimating the term…
Devices for treatments of diseases and disorders associated with the gastrointestinal tract, especially the stomach, or urinogenital tract are described herein. Initially, the device is in a temporary form which is suitable for oral or rectal administration. After exposure to a stimulus, such as a temperature or pH change, the device changes shape to a permanent form, which allows it to become mechanically fixed in the stomach, esophagus or intestine. In one embodiment, the device is used to reduce the volume of the stomach, esophagus or intestine without interfering with the flow of the food through the gastrointestinal tract. The device may be used to help overweight patients lose weight and to deliver drugs to treat disorders and diseases in the in the stomach or intestine. The devices are manufactured from a stimuli-sensitive polymeric material, which is biocompatible and primarily adapted to the mechanical properties and geometry in the area to which it is applied. In the preferred embodiment, the material is a shape memory polymer. Depending on the desired application, the polymer may be either biodegradable or non-degradable.
A device to treat diseases and disorders of the gastrointestinal or urinogenital tract comprising a shape memory polymer having a first temporary form allowing the device to be inserted and a second permanent form to retain the device within the gastrointestinal or urogenital tract.
A method for treating diseases and disorders of the gastrointestinal tract or urogenital tract comprising orally administering a composition to a patient, wherein the composition comprises a device comprising a shape memory polymer, and exposing the device to a stimulus which changes the form of the device.
Dependencies are inferred from the claim text.