Bismuth dithiocarbamate compounds and uses thereof
OwnerEdward Tiekinkinventor
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Abstract
The present invention relates to bismuth dithiocarbamate compounds of general formula I: wherein R and R1 are the same or different, and each is an alkyl, substituted alkyl, aryl or a substituted aryl; X is a halide or a pseudo-halide; and n is either 2 or 3, for use as an active pharmaceutical substance. In particular, they can be used as anti-tumour agents and for the treatment of various forms of tumours. Also provided are some novel bismuth dithiocarbamate compounds and the process for preparing these compounds.
Claims19
1-20. (canceled)
A pharmaceutical composition comprising the compound of general formula I:
- wherein R and R1 are the same or different, and each is an alkyl, substituted alkyl, aryl or a substituted aryl;
- X is a halide or a pseudo-halide;
- and n is either 2 or 3;
- for use as an active pharmaceutical substance.
A bismuth dithiocarbamate compound of general formula II:
- wherein NRR′=N(CH2)4, X is Cl.
A method for treating tumor comprising the administration of compound of general formula I:
- wherein R and R1 are the same or different, and each is an alkyl, substituted alkyl, aryl or a substituted aryl;
- X is a halide or a pseudo-halide;
- and n is either 2 or 3.
Dependencies are inferred from the claim text.