Back to results
US 2006/0142450 A1Published application
Process for preparation of nerol oxide
AssigneeCouncil of Scientific and Industrial Research
InventorsVijay Sethi, Samar Andotra, Subhash Taneja, Pankaj Gupta, Ghulam Qazi
Life of this patent
Estimating the term…
Abstract
The presert invention relates to a process for the synthesis of racemic nerol oxide i.e. 3,6-dihydro-4-methyl-2-[2-methyl-1-propenyl)-2H-pyran from monoterpene alcohol nerol i.e. cis-3,7-dimethylocta-2,6-diene-1-ol.
Claims18
A process for the preparation of racemic nerol oxide of formula 1 from monoterpene nerol of formula 2, the process comprising;
- (i) haloalkoxylatin monote e nerol of formula 2 with a halogenating agent and in a solvent to produce 7-alkoxy-3,7-dimethyl-6-halo-2-octenol of formula 3 where R is alkyl and X is halo;
- (ii) dehydrohaltgenating the compound of formula 3 to obtain a 7-alkoxy-3,7-dimethyl-octa-2,5-dien-1-ol derivative of formula 4 where R is as stated above;
- and
- (iii) converting the octadienol of formula 4 to produce racemic nerol oxide of formula 1.
1 more element
Dependencies are inferred from the claim text.