2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivative

A 2-amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivative, a pharmaceutically acceptable salt thereof or a hydrate thereof, represented by formula [I]

• [wherein R1 and R2 are the same or different, and each represents a hydrogen atom, a C1-10alkyl group, a phenyl group, a naphthyl group, a C1-10alkyl group substituted by one or two phenyl groups, a C2-10alkenyl group, a C2-10alkynyl group, a hydroxylC2-10alkyl group, a C1-10alkoxycarbonylC1-10alkyl group, an aminoC2-10alkyl group or a C1-10alkoxyC1-10alkyl group;
• X represents a hydrogen atom or a fluorine atom;
• Y represents an amino group, —SR3, —S(O)nR7, —SCHR3R4, —S(O)nCHR3R4, —NHCHR3R4, —N(CHR3R4)(CHR5R6), —NHCOR3 or —OCOR7 (wherein R3, R4, R5 and R6 are the same or different, and each represents a hydrogen atom, a C1-10alkyl group, a phenyl group, a naphthyl group, a naphthyl group substituted by one to seven halogen atoms or a hetroaromatic group, or represents “a phenyl group substituted by one to five substituents selected from a group consisting of a halogen atom, a phenyl group, a C1-10alkyl group, a C1-10alkoxy group and a trifluoromethyl group”;
• R7 represents a C1-10alkyl group, a phenyl group, a naphthyl group, a naphthyl group substituted by one to seven halogen atoms or a hetroaromatic group, or represents “a phenyl group substituted by one to five substituents selected from a group consisting of a halogen atom, a phenyl group, a C1-10alkyl group, a C1-10alkoxy group and a trifluoromethyl group”;
• and n represents integer 1 or 2)].