Use of formaldehyde and formaldehyde-releasing compounds in a composition for controlling mycobacteria

Use of a bactericide selected from formaldehyde and formaldehyde-releasing compounds in a composition for controlling mycobacteria, characterized in that the activity of the bactericide against mycobacteria is greater at the same concentration than the activity of 2,2′,2″-(hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol or the same activity against mycobacteria as using 2,2′,2″-(hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol is achieved at a lower concentration of the bactericide.

Use according to claim 7, characterized in that the formaldehyde-releasing compound is selected from 3,3′-methylenebis[5-methyloxazolidine], 1,3-bis(hydroxymethyl)urea, (ethylenedioxy)dimethanol, 2-(2-butoxyethoxy)ethoxymethanol, tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, α,α′,α″-trimethyl-1,3,5-triazine-1,3,5-(2H,4H,6H)-triethanol and mixtures thereof.

Use according to claim 7, characterized in that the bactericide is used in a mixture with one or more other active compounds selected from 3-iodo-2-propinylbutyl carbamate, N-cyclohexyl-N-nitrosohydroxylamine salts (preferably the potassium salt), phenols such as o-phenylphenol, isothiazol-3-ones such as 5-chloro-2-methyl-2H-isothiazol-3-one and/or 2-methyl-2H-isothiazol-3-one, 1,2-benzisothiazol-3(2H)-one, n-butyl-1,2-benzisothiazol-3(2H)-one and 2-octyl-3(2H)-isothiazol-3-one and also salts of 2-mercaptopyridine N-oxide, such as the sodium or zinc salt (Pyrion-Na, Zn-pyrithione), preferably in a mixture with Pyrion-Na, 1,2-benzisothiazol-3(2H)-one or 2-octyl-3(2H)-isothiazol-3-one.

Use according to claim 7, characterized in that the mycobacterium is selected from M. chelonae, M. immunogenum, M. abscessus, M. avium and M. terrae, preferably M. chelonae and M. immunogenum.

Use of isothiazol-3-ones to increase the mycobactericidal activity of formaldehyde and formaldehyde-releasing compounds.