Method of controlling telomere length
OwnerKunihiro Ohta, Takehiko Shibatainventors
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Abstract
A method of controlling telomere length wherein the method comprises introducing into a cell a DNA encoding Mre11 protein or a DNA encoding a protein comprising Mre11 protein wherein a part of the nuclease domain, the C-terminal domain or the whole thereof is modified or deleted.
Claims26
A method of controlling telomere length wherein the method comprises modifying physiological activity of endogenous Mre11 protein in a eukaryotic cell.
An agent for controlling telomere length comprising as an active component a substance which modifies physiological activity of endogenous Mre11 protein in a eukaryotic cell.
A gene therapeutic agent for a telomere length-associated disease comprising as an active agent a substance which modifies physiological activity of endogenous Mre11 protein in a eukaryotic cell.
Dependencies are inferred from the claim text.