Compositions capable of reducing elevated blood urea concentration
OwnerRobbert Benner, Nisar Khaninventors
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Abstract
The invention includes a method of reducing urea concentration in a subject's serum. Such a method comprises administering to the subject (e.g., a mammal such as a human) a composition comprising an oligopeptide (or oligopeptides) having activity in reducing urea concentration in the subject's serum as determined by a mouse renal reperfusion test, wherein the oligopeptide comprises the sequence AQG or MTRV (SEQ ID NO: 1), AQGV (SEQ ID NO:2) or LAGV (SEQ ID NO:4).
Claims24
A method of reducing blood urea nitrogen concentration in a subject's serum, the method comprising:
- administering to the subject a composition comprising an oligopeptide having activity in reducing blood urea nitrogen concentration in the subject's serum as determined by a mouse renal ischemia reperfusion test,
- said oligopeptide comprising a sequence AQG, MTRV (SEQ ID NO:1), or LAGV (SEQ ID NO:4).
A composition for reducing blood urea nitrogen concentration in a subject's serum, said composition comprising:
- an oligopeptide having activity in reducing blood urea nitrogen concentration in a subject's serum as determined by a mouse renal ischemia reperfusion test, said oligopeptide comprising the sequence AQG, MTRV (SEQ ID NO:1) or LAGV (SEQ ID NO:4) in an amount sufficient to reducing blood urea nitrogen concentration in a subject's serum.
Dependencies are inferred from the claim text.