Protein based oral lubricant
AssigneePacific Biolink Pty. Limited
InventorDennis Bannister
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Abstract
The present invention relates to formulations containing phosphoprotein, designed for use as oral lubricant or as artificial saliva, methods of using the formulations and processes for the preparation of the formulations.
Claims39
A formulation for the lubrication of the oral cavity in humans or animals, wherein said formulation comprises a water-soluble or water-dispersible form of at least one isolated and purified casein phosphoprotein, or salt thereof.
A formulation for the lubrication of the oral cavity in humans or animals, wherein said formulation comprises, a water-soluble or water-dispersible form of at least one isolated and purified casein phosphoprotein, or salt thereof, complexed with at least one bioactive constituent, wherein the bioactive constituent is selected from the group consisting of calcium phosphate and calcium phosphate admixed with at least one other bioactive.
A method for lubrication of the oral cavity of a human or animal wherein said method comprises administration to said human or animal of a therapeutically effective amount of a formulation comprising a water-soluble or wafer-dispersible form of at least one isolated and purified casein phosphoprotein, or salt thereof.
A method for the lubrication of the oral cavity of a human or animal wherein said method comprises administration to said human or animal of a therapeutically effective amount of a formulation comprising a water-soluble or water-dispersible form of at least one isolated and purified casein phosphoprotein, or salt thereof, complexed with at least one bioactive constituent, wherein the bioactive constituent is selected from the group consisting of calcium phosphate and calcium phosphate admixed with at least one other bioactive.
A process for the preparation of an oral lubrication formulation, wherein said process comprises:
- (i) adding a water-soluble or water-dispersible form of at least one casein phosphoprotein, and phosphate ions, to an aqueous solution and stirring until the casein is dispersed;
- (ii) adding an aqueous solution of calcium ions, with stirring, to the solution formed in part (i), at a pH of 6.5 or greater, and optionally;
- (iii) spray drying the product of step (ii).
A process for the preparation of an oral lubrication formulation, wherein said process comprises:
- (i) adding a water-soluble or water-dispersible form of at least one casein phosphoprotein to an aqueous solution and stirring until the casein is dispersed;
- and optionally (ii) spray drying the product of step (i).
Dependencies are inferred from the claim text.