Method and composition for treatment and/or prevention of antibiotic-resistant microorganism infections
AssigneeSa Majeste la Recherche el Developpement sur le bovin laitier et le porc
InventorsMoussa Diarra, Pierre LaCasse, Denis Petitclerc
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Abstract
The present invention related to a new composition, use and method to improve the cure of infections caused by antibiotic resistant microbial pathogens, in particular beta-lactam resistant microorganisms. Lactoferrin (LF) or Lactoferricin (LFC) can be administrated alone or in combination with antibiotic to affect growth, physiology and morphology of targeted microorganism. Lactoferrin increased susceptibility and can reverse resistance of microorganism to antibiotics.
Claims14
1-29. (canceled)
A pharmaceutical composition useful for effecting β-lactamase inhibition in humans and animals which comprises a β-lactamase inhibitory amount of lactoferricin or lactoferrin or a fragment thereof, in combination with a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.