Microarray devices having controllable reaction volume
AssigneeCapitalBio Corporation
InventorsWanli Xing, Fei Xian, Xianhua Wang, Jing Cheng
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Abstract
This invention relates generally to the field of microarray reaction devices and uses thereof. In particular, the invention a microarray reaction device wherein a plurality of reaction spaces are formed between a first and second plurality of projections, the heights of said plurality of reaction spaces being substantially identical and controllable by a supporting structure, and the relative positions between the first and second plurality of projections being controllable by a positioning structure. Articles of manufacture comprising the microarray reaction device and methods for assaying an analyte using the microarray reaction device are also provided.
Claims48
A microarray reaction device, which device comprises:
- a) a microarray chip comprising a first plurality of projections;
- b) a cover comprising a second plurality of projections;
- c) a supporting structure on said microarray chip and/or said cover;
- and
- d) a positioning structure on said microarray chip and/or said cover,
- wherein a plurality of reaction spaces are formed between at least some first projections and at least some second projections, the heights of said plurality of reaction spaces being substantially identical and controllable by the height of said supporting structure, and the relative positions between said first plurality of projections and said second plurality of projections being controllable by said positioning structure.
Dependencies are inferred from the claim text.