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US 2006/0141564 A1Published application
Nucleic acids encoding duramycin
AssigneeMolichem Medicines, Inc.
InventorsLuis Molina, Charles Romeo
Life of this patent
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Abstract
Nucleic acids encoding preduramycin and produramycin are described, along with recombinant nucleic acids and host cells containing the same and methods of use thereof, such as for the manufacture of the lantibiotic duramycin.
Claims14
An isolated nucleic acid selected from the group consisting of:
- (a) a nucleic acid according to SEQ ID NO:
- 2 encoding preduramycin;
- (b) a nucleic acid according to SEQ ID NO:
- 4 encoding produramycin;
- (c) nucleic acids that are at least 95 percent identical in sequence to nucleic acids of (a) or (b) above and which encode preduramycin or produramycin;
- (d) nucleic acids that differ from the nucleic acids of (a), (b), or (c) above due to the degeneracy of the genetic code, and which encode a preduramycin or produramycin encoded by a nucleic acid of (a), (b), or (c) above.
3 more elements
Dependencies are inferred from the claim text.