Chlamydia pneumoniae associated chronic intraocular disorders and treatment thereof
OwnerMurat Kalayogluinventor
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Abstract
Infection by Chlamydia pneumoniae has been identified as a risk factor associated with the pathogenesis of certain chronic intraocular disorders, for example, age-related macular degeneration. The invention provides methods of identifying individuals at risk of developing chronic intraocular disorders, and methods of delaying and/or preventing the onset of such chronic intraocular disorders.
Claims28
A method of determining whether a mammal is at risk of developing, or has, a chronic intraocular disorder, the method comprising:
- detecting in a sample from the mammal the presence of Chlamydia pneumoniae or a Chlamydia pneumoniae specific agent, the presence of which is indicative that the mammal is at risk of developing, or has, the chronic intraocular disorder.
A method of determining whether a human is at risk of developing, or has, age-related macular degeneration, the method comprising:
- detecting in a sample from the human the presence of Chlamydia pneumoniae or a Chlamydia pneumoniae specific agent, the presence of which is indicative that the human is at risk of developing, or has, age-related macular degeneration.
A method of preventing, slowing or stopping the progression of a chronic intraocular disorder, the method comprising the step of:
- administering to a mammal suspected of having or developing a chronic intraocular disorder an effective amount of an anti-Chlamydia pneumoniae agent thereby to prevent, slow or stop the progression of the disorder.
A kit comprising an agent for detecting Chlamydia pneumoniae or a Chlamydia pneumoniae specific agent and instructions on how to detect Chlamydia pneumoniae or a Chlamydia pneumoniae specific agent in a sample to determine if a mammal is at risk of developing, or has, a chronic intraocular disorder.
Dependencies are inferred from the claim text.