Back to results
US 2006/0141464 A1Published application
Method for immobilizing biologic molecules on solid surfaces
OwnerMarcella Chiariinventor
Life of this patent
Estimating the term…
Abstract
The invention provides a method for immobilization of biological molecules such as nucleic acids, peptides and proteins onto the surface of a glass or plastic solid support.
Claims19
A polymer for the immobilization of biological molecules onto a solid support, obtainable by copolymerization of a mixture comprising:
- a) a monomer selected from acrylamide and methacrylamide, optionally mono-or di-substituted on the nitrogen by C1-C12 linear or branched alkyl chains which in turn can be substituted by a halogen, preferably fluorine, or by a methoxy group or, in the case of N-mono substituted compounds, by a hydroxy group;
- b) an ethylene or acrylic monomer linked by means of C1-C6 alkyl chains optionally interrupted by O, N or S atoms, to functional groups able to covalently react with amines, thiols or hydroxyls present on a protein/peptide, or with the amino-modified residue of a nucleic acid.
A method for coating a plastic or glass surface, which comprises contacting an aqueous solution of a polymer as claimed in any of the above claims with said surface for a time sufficient for polymer adsorption.
Dependencies are inferred from the claim text.