Substrates, devices, and methods for cellular assays
OwnerChristopher Murphy, Barbara Israel +1inventors
InventorsChristopher Murphy, Barbara Israel, Nicholas Abbott
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Abstract
The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assay format.
Claims20
1-94. (canceled)
An apparatus comprising, a substrate having thereon at least one assay region, wherein said at least one assay region is configured to culture cells and comprises an optically opaque region and an optically transparent region.
109-201. (canceled)
An apparatus comprising a substrate having thereon a plurality of assay regions, wherein said plurality of assay regions are configured to culture cells and comprises an optically opaque region and an optically transparent region.
An apparatus comprising a substrate having thereon a plurality of assay regions, wherein said plurality of assay regions comprise an optically opaque region and an optically transparent region and are configured to culture cells and for readouts selected from the group consisting of colorimetric, fluorimetric, optical density, and light scattering readouts.
Dependencies are inferred from the claim text.