Methods and compositions for delivery of catecholic butanes for treatment of obesity
AssigneesErimos Pharmaceuticals LLC, The Johns Hopkins University
InventorsJonathan Heller, Neil Frazier, Chih-Chuan Chang, Elaine Lin, Ru Huang
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Abstract
The present invention provides kits, methods and compositions for the treatment of obesity. The compositions herein contain a substantially pure preparation of at least one catecholic butane, including, for example, NDGA compounds in a pharmaceutically acceptable carrier or excipient. The catecholic butane such as NDGA or its derivatives are administered to one or more subjects in need of treatment.
Claims71
A method of treating obesity in a subject in need of such treatment comprising the steps of
- (a) providing a composition comprising at least one catecholic butane and a pharmaceutically acceptable carrier or excipient;
- and
- (b) administering the composition to the subject in a therapeutically effective amount to treat the obesity.
A method of treating obesity in a subject in need of such treatment, comprising the steps of:
- (a) providing a composition comprising a catecholic butane selected from the group consisting of tri-O methyl NDGA and tetra-O-methyl NDGA, and a pharmaceutically acceptable carrier or excipient;
- and
- (b) administering to the subject the composition in an amount effective to treat the obesity.
A kit for treatment of obesity comprising a comprising at least one catecholic butane and a pharmaceutically acceptable carrier or excipient, and instructions for administration of the composition to treat the obesity.
Dependencies are inferred from the claim text.