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US 2006/0141033 A1Published application
P-glycoprotein inhibitor comprising octilonium bromide as an effective ingredient
OwnerHesson Chung, Seo-Young Jeong +4inventors
InventorsHesson Chung, Seo-Young Jeong, Ick-Chan Kwon, Yeong-Taek Park, In-Hyun Lee, Soon-Hong Yuk
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Abstract
The present invention relates to a new use of octylonium bromide as p-glycoprotein inhibitor to increase cellular uptake of drugs. More particularly, the present invention provides octylonium bromide as a p-glycoprotein inhibitor to increase cellular uptake of drugs such as anticancer drugs by taking octylonium bromide simultaneously with or proceding drug administration.
Claims11
A p-glycoprotein inhibitor containing octylonium bromide as an effective ingredient to increase the absorption of drugs into the cell.
Dependencies are inferred from the claim text.