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US 2006/0141031 A1Published application
Orally disintegrating pharmaceutical compositions with sensory cue agents
OwnerDennis Nelson, William Nicholsinventors
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Abstract
The present invention relates to pharmaceutical compositions that disintegrate in the mouth and include at least one systemically active pharmaceutical ingredient in a therapeutically effective amount and at least one sensory cue agent in a sensory effective amount.
Claims20
A pharmaceutical composition comprising:
- (a) at least one systemically active pharmaceutical ingredient in a therapeutically effective amount;
- and
- (b) at least one sensory cue agent in a sensory cue effective amount;
- wherein said pharmaceutical composition is designed to disintegrate in the buccal cavity in less than about 60 seconds.
1 more element
A pharmaceutical composition comprising:
- (a) at least one systemically active pharmaceutical ingredient in a therapeutically effective amount;
- wherein said active pharmaceutical ingredient is selected from the group consisting of phenylephrine, pseudoephedrine, dextromethorphan, diphenhydramine and combinations thereof and
- (b) at least one sensory cue agent in a sensory cue effective amount;
- wherein said sensory cue agent is selected from the group consisting of menthol oil, menthol crystals, mannitol, eucalyptus oil, eucalyptol, thymol, camphor, spearmint, cinnamon, mint, ginger, wintergreen (methyl salicylate), peppermint, carboxamides, acyclic carboxamides, 3-1-menthoxy propane-1,2-diol, N-substituted-p-menthane-3-carboxamides, N-ethyl-p-menthane-3-carboxamide, N,2,3-trimethyl-2-isopropylbutanamide and combinations thereof;
- wherein said pharmaceutical composition is a tablet designed to disintegrate in the buccal cavity in less than about 60 seconds.
2 more elements
A packaged kit for a patient comprising:
- a housing of a plurality of oral dosage forms comprising a pharmaceutical composition comprising:
- (a) at least one systemically active pharmaceutical ingredient in a therapeutically effective amount;
- and
- (b) at least one sensory cue agent in a sensory cue effective amount;
- wherein said pharmaceutical composition is designed to disintegrate in the buccal cavity in less than about 60 seconds, and;
- instructions for carrying out drug administration therewith.
3 more elements
Dependencies are inferred from the claim text.