Sublingual administration of non-steroidal anti-inflammatory pharmacological substances
OwnerValerio Cioliinventor
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Abstract
The present invention relates to a sublingual administration method of non-steroidal ant-inflammatory, referred as FANS, which allows to considerably reduce the therapeutic dose, with the additional advantage of increasing the quickness of the effects and improving the tolerability.
Claims10
Pharmaceutical formulation including a non-steroidal anti-inflammatory agent (FANS), characterized in that said formulation is administered by sublingual route and is such to promote the fast disintegration thereof in the oral cavity and is able to exert an anti-inflammatory activity at considerable reduced doses with respect to an oral formulation containing the same anti-inflammatory agent.
Formulation according to at least one of the preceding claims, characterized in that the non-steroidal anti-inflammatory agent FANS is preferably selected among:
- nimesulide, ketoprofen, ibuprofen, paracetamol, diclofenac, naproxen, ketorolac, tenoxicam or pyroxicam.
Formulation according to at least one of the preceding claims, characterized in that said formulation is in a pharmaceutical form selected among:
- gel, granulate, powder, freeze-dried product, pressed capsule or pill.
Use of at least a non-steroidal anti-inflammatory agent FANS for the preparation of a sublingual pharmaceutical formulation for the treatment of inflammatory symptoms of various type, generally associated with pain and fever.
Dependencies are inferred from the claim text.