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AssigneesErimos Pharmaceuticals LLC, The Johns Hopkins University
InventorsRu Huang, Richard Park, Chih-Chuan Chang, Yu-Chuan Liang, David Mold, Elaine Lin, Jonathan Heller, Neil Frazer
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The present invention provides kits, methods and compositions for the treatment of tumor and other proliferative diseases such as tumors. The compositions herein contain a substantially pure preparation of at least one catecholic butane, including, for example, NDGA compounds in a pharmaceutically acceptable carrier or excipient. The catecholic butane such as NDGA or its derivatives are administered to one or more subjects in need of treatment by a route other than direct injection into the affected tissues or topical application on affected tissues.
A pharmaceutical composition for treatment of a disease in a subject comprising at least one catecholic butane other than NDGA and a pharmaceutically acceptable carrier or excipient, wherein the pharmaceutical composition is formulated for delivery by a route other than by direct injection into an affected tissue or topical application onto skin.
The pharmaceutical composition of claim 10, wherein the composition is formulated for one selected from the group consisting of slow release and quick release capsules.
A method of treatment of a disease in a subject comprising the steps of:
A method of treating a malignant, premalignant or benign tumor in a subject arising from or associated with a tissue or organ selected from the group consisting of breast, liver, stomach, pancreas, colorectal, colon and prostate, comprising the steps of:
Dependencies are inferred from the claim text.