Lansoprazole formulations and related processes and methods
OwnerZhong Zhang, Orn Almarsson +1inventors
InventorsZhong Zhang, Orn Almarsson, Hongming Chen
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Abstract
The invention provides novel liquid lansoprazole formulations comprising lansoprazole and an excipient system, wherein: (a) the concentration of lansoprazole in the formulations ranges from about 0.3 mg/mL to about 50 mg/mL; (b) the excipient system comprises either a single excipient, or a combination of two to four compositionally distinct excipients; and (c) the formulations may be administered parenterally to a mammal to treat or prevent a gastrointestinal disorder.
Claims26
1-84. (canceled)
A liquid lansoprazole formulation comprising lansoprazole and an excipient system, wherein:
- (a) the concentration of lansoprazole in the formulation ranges from about 0.3 mg/mL to about 50 mg/mL;
- (b) the excipient system comprises either a single excipient, or a combination of two to four compositionally distinct excipients, wherein each excipient is'selected from the group of excipient categories consisting of:
- a hydrotrope, a preservative, a pharmaceutically acceptable salt, a surfactant, a base, a cyclodextrin, a viscosity modifier, an emulsifier, a solvent, a carrier, and a lubricant;
- and
- (c) the formulation may be administered parenterally to a mammal in need thereof.
Dependencies are inferred from the claim text.