Novel human protein kinases and protein kinase-like enzymes
AssigneeSugen, Inc.
InventorsGregory Plowman, David Whyte, Gerard Manning, Sucha Sudarsanam, Ricardo Martinez
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Abstract
The present invention relates to kinase polypeptides, nucleotide sequences encoding the kinase polypeptides, as well as various products and methods useful for the diagnosis and treatment of various kinase-related diseases and conditions. Through the use of a bioinformatics strategy, mammalian members of the PTK's and STK's have been identified and their protein structure predicted.
Claims5
1-9. (canceled)
An antibody or antibody fragment having specific binding affinity to a kinase polypeptide or to a domain of said polypeptide, wherein said polypeptide is a kinase polypeptide having an amino acid sequence selected from the group consisting of those set forth in SEQ ID NO:
- 13, SEQ ID NO:
- 14, SEQ ID NO:
- 15, SEQ ID NO:
- 16, SEQ ID NO:
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- 23, and SEQ ID NO:
- 24.
A hybridoma which produces an antibody having specific binding affinity to a kinase polypeptide having an amino acid sequence selected from the group consisting of those set forth in SEQ ID NO:
- 13, SEQ ID NO:
- 14, SEQ ID NO:
- 15, SEQ ID NO:
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- 17, SEQ ID NO:
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- 20, SEQ ID NO:
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- 22, SEQ ID NO:
- 23, and SEQ ID NO:
- 24.
13-28. (canceled)
Dependencies are inferred from the claim text.