Nephropathy-associated gene
AssigneeAkari Inada
InventorsAkari Inada, Atsushi Fukatsu, Yutaka Seino
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Abstract
A nephropathy-associated gene which encodes a transcription repressor; and a nonhuman transgenic animal suffering from nephropathy which is constructed by transferring the above gene and allows the observation of increases in urinary volume, urinary albumin and urinary NAG, pyelectasis, enlargement in kidney tubule and glomerular swelling at the early stage and the following sclerosis.
Claims31
A nephropathy-associated gene comprising a nucleic acid encoding an insulin transcription repressor belonging to a transcription factor CREM family.
A nephropathy-associated protein having an activity of an insulin transcription repressor belonging to a transcription factor CREM family.
Dependencies are inferred from the claim text.