Aerosol pharmaceutical compositions
OwnerHeng Changinventor
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Abstract
A suspension aerosol composition suitable for use in pressurized metered dose inhalers has improved post-shaking suspension stability and comprises predetermined amounts of an active pharmaceutical ingredient (API) insoluble in the composition, a propellant comprising a hydrofluoroalkane (HFA), and a pharmaceutically acceptable non-aminated C1-6 organic acid.
Claims20
A composition for use in a metered dose inhaler (MDI), the composition comprising predetermined amounts of an active pharmaceutical ingredient (API) insoluble in the composition, a propellant comprising a hydrofluoroalkane (HFA), and a pharmaceutically acceptable non-aminated C1-6 organic acid that increases post-shaking suspension time of the API in the composition to at least 30 seconds to provide uniform dosing of the API from the inhaler over at least 30 seconds post-shaking.
Dependencies are inferred from the claim text.