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US 2006/0140870 A1Published application
Method for assessing tumor response to cancer treatment
AssigneeGeneral Electric Company
InventorsEgidijus Uzgiris, Mohan Amaratunga, Brian Grimmond, Daniel Meyer
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Abstract
A method for measuring tumor response to a cancer therapy is provided. The method comprises the steps of injecting a polymeric contrast agent in a subject; obtaining a series of magnetic resonance image signals of the contrast agent in the tumor for up to about 60 minutes; and determining a slope of the magnetic resonance image signal as a function of time.
Claims17
A method for measuring tumor response to a cancer treatment comprising the steps of:
- a) injecting a polymeric contrast agent in a subject;
- b) obtaining a series of magnetic resonance image signals of the contrast agent in the tumor for up to about 60 minutes;
- and
- c) determining a slope of the magnetic resonance image signal as a function of time.
1 more element
A method for measuring tumor response to a cancer therapy comprising the steps of:
- a) injecting in a subject a homopolymer of lysine wherein lysine residues are substituted with Gd-DTPA;
- b) obtaining a series of magnetic resonance image signals of the contrast agent in the tumor for up to about 60 minutes;
- c) determining a slope of the magnetic resonance image signal as a function of time;
- d) determining the tumor signal at time 0;
- e) treating the subject with a cancer treatment;
- f) repeating steps a) through d) at least 24 hours after the initial cancer treatment;
- and
- g) comparing the first and second measurement to assess tumor response to the cancer therapy.
5 more elements
Dependencies are inferred from the claim text.