Sorbent and process of solid phase extraction

Abstract

A sorbent comprising a spherical, highly porous polymer with specific hydrophobic-hydrophilic properties, specific pore volume and its distribution, as well as a method of solid phase extraction using said sorbent. The sorbent is produced by suspension polymerization of at least one hydrophilic monomer and at least one hydrophobic monomer, where the hydrophilic monomer comprises an imidazole moiety and the hydrophobic monomer is a mixture of isomeric divinylbenzene monomers and isomeric ethylvinylbenzene monomers. The sorbent has a pore diameter range from 5 Å to 1000 Å, an average pore diameter of 50 Å to 250 Å, and a pore volume from 1 ml/g to 2 ml/g comprising 15% to 25% micropores, 50% to 80% mesopores, and 5% to 30% macropores. Solid phase extraction columns and plates packed with the sorbent of this invention provide reliable high recoveries for a broad spectrum of analytes with various polarity, even if the sorbent is dried out multiple times during the extraction.

Dependencies are inferred from the claim text.