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US 2006/0137207 A1Published application
Flavonoid compounds as therapeutic antioxidants
AssigneeAntoxis Limited
InventorsStuart Caldwell, Christopher Bennett, Richard Hartley, Donald McPhail, Garry Duthie
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Abstract
Novel flavonoid compounds having anti-oxidant activity are described. Formula 1. The compounds have been shown to exhibit anti-oxidative properties in biological systems and their utility in a sunscreen or skincare composition or to treat conditions involving oxidative damage, especially curative or prophylactic treatment of Alzheimer's disease or ischaemia-reperfusion injury, is described.
Claims45
A compound of the following Formula 1:
- wherein
- RA is a C2 to C30 saturated or unsaturated hydrocarbon chain;
- R10, R11, R13, R14 and R3 each independently represent H, OH, a C1-6 ether, or a saturated or unsaturated hydrocarbon chain which may be substituted with one or more of nitro, halogen, amino, hydroxyl, ketone or aldehyde group;
- optionally there is a double bond between C2 and C3 of the C ring;
- n represents 0 or 1;
- and
- RB is a C2 to C15 saturated or unsaturated hydrocarbon chain, and where RB is present, RA and RB are both C2 to C12 aliphatic alkyl chains.
4 more elements
The compound of claim l, as claimed in any one of
- wherein RA has the following structure:
- wherein
- n is an integer from 1 to 7;
- and
- m is an integer from 1 to 7.
2 more elements
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Dependencies are inferred from the claim text.