Autologous Growth Factors to Promote Tissue In-Growth in Vascular Device
AssigneeMedtronic Vascular, Inc.
InventorsJack Chu, Scott Doig, Brian Fernandes, Trevor Huang, Josiah Wilcox
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Abstract
Methods and devices for ameliorating stent graft migration and endoleak using treatment site-specific cell growth promoting compositions in combination with stent grafts are disclosed. Also disclosed is coating of autologous growth factor compositions onto stent grafts prior to stent graft implantation. Additional embodiments include stent grafts having autologous growth factor composition coatings useful for treating aneurysms.
Claims19
A method for providing a stent graft and a cell growth-promoting composition comprising:
- obtaining autologous platelet rich plasma (PRP) from a patient in need of a stent graft;
- activating said PRP to form autologous growth factor composition;
- coating said stent graft with said autologous growth factor composition;
- and
- implanting said autologous growth factor composition-coated stent graft into a vessel at a treatment site in a patient wherein said autologous growth factor composition-coated stent graft induces endothelialization of said stent graft.
A delivery catheter for delivering a stent graft to a vessel in a patient in need thereof, having disposed therein a stent graft, comprising at least one injection port through which coating composition(s) are injected to coat said stent graft.
An endothelialization promoting stent graft for implantation into a patient in need thereof comprising a stent graft having an autologous growth factor composition deposited thereon.
Dependencies are inferred from the claim text.