Tissue graft prosthesis devices containing juvenile or small diameter submucosa
OwnerF. Obermiller, Michael Hiles +1inventors
InventorsF. Obermiller, Michael Hiles, Jason Hodde
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Abstract
Described are preferred tissue graft materials that incorporate juvenile submucosa tissue from a warm-blooded vertebrate. Preferred materials incorporate juvenile small intestinal submucosa tissue from a mammal such as a porcine mammal, and the constructs are preferably in tubular form and utilized the isolated submucosa tissue in its native, intact tubular form. More preferred devices are multi-laminate and include the juvenile submucosa tissue in addition to at least one, and preferably several other layers providing increased strength or other advantageous properties to the construct.
Claims40
A tubular graft construct, comprising:
- a tubular element having walls and a lumen;
- and
- said walls including juvenile submucosa tissue from a warm-blooded vertebrate.
A tissue graft composition, comprising juvenile submucosa tissue.
A method for tissue grafting in a mammal, comprising grafting said mammal with a tissue graft material comprising juvenile submucosa tissue.
A tubular graft construct, comprising:
- a tubular element having walls and a lumen;
- said walls including at least a first layer formed with intact tubular submucosa having a native internal diameter no greater than about 12 mm.
Dependencies are inferred from the claim text.