Process for purifying diacerein
OwnerDomenico Maggiinventor
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Abstract
A process for obtaining diacerein with an aloe-emodine content lower thatn 100 ppm, prefereably of 0-5 ppm, is herein disclosed. The process comprises subjecting an an aqueous-organic solution of a diacerein salt with a weak base to extraction with a water immiscible or sparingly water-miscible solvent, such as toluene, aetates of C2-C4 alcohols, halohydrocarbons and the like.
Claims15
A process for obtaining diacerein with a content of aloe-emodine and mono-, di- and tri-acetyl derivatives thereof lower than 100 parts per million, characterized in that an aqueous-organic solution of a diacerein salt with a weak base is extracted with a water immiscible or sparingly water-miscible solvent.
Dependencies are inferred from the claim text.