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US 2006/0135785 A1Published application
Alpha-phenyl acetanilide derivatives having an acat inhibiting activity and the therapeutic application thereof
AssigneePierre Fabre Medicament
InventorsJean-Francois Patoiseau, Jean-Marie Autin, Andre Delhon, Didier Junquero
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Abstract
The present invention relates to novel analide derivatives of formula I, enantiomers and stereoisomers thereof, and their pharmaceutically acceptable salts. The invention also relates to pharmaceutical compositions containing the compounds and methods of treating hypercholesterolemia and atherosclerosis therewith.
Claims11
An anilide derivative having the general formula I:
- wherein:
- R1 is a hydroxyl or amino group;
- R2 is a hydrogen or methyl radical;
- R3 is a hydrogen or a fluorine atom;
- and,
- wherein A is
- or
- wherein:
- n is an integer from 5 to 11, limits inclusive, and
- R4 and R5, are independently a hydrogen or a fluorine atom;
- and
- enantiomers or stereoisomers of said analide derivative, and pharmaceutically acceptable salts thereof.
9 more elements
Dependencies are inferred from the claim text.