Deuterated catecholamine derivatives and medicaments comprising said compounds
AssigneeBDD Berolina Drug Development GmbH
InventorRudolf-Giesbert Alken
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Abstract
The present invention concerns deuterated catecholamine derivatives as well as pharmaceuticals containing these compounds. In addition, the invention concerns the use of deuterated catecholamine derivatives as well as physiologically compatible salts thereof, and also pharmaceutical compositions, which contain these compounds, also in combination with enzyme inhibitors, for the treatment of dopamine deficiency diseases or diseases which are based on disrupted tyrosine transport or disrupted tyrosine decarboxylase, as well as other disorders.
Claims42
Deuterated catecholamine derivatives of the general formula I
- wherein
- R1 is H or D, R2 indicates H or D, R3 is H, D, C1-C6 alkyl or C5 to C6-cycloalkyl, deuterated C1 to C6-alkyl or C5 to C6-cycloalkyl, R4 indicates H or D and R5 is H or D.
12-33. (canceled)
Dependencies are inferred from the claim text.