Remedy for chronic disease
AssigneeOno Pharmaceuticals Co., Ltd.
InventorsShinji Nakade, Hiromu Habashita, Takuya Seko
Life of this patent
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Abstract
A remedy and/or a preventive for a chronic disease which contains an EDG-2 antagonist. Because of binding to a subtype EDG-2 of LPA receptor, an EDG-2 antagonist is useful in treating and/or preventing chronic diseases (for example, diseases caused by the progress of chronic asthma, glomerular nephritis, obesity, arteriosclerosis, rheumatoid and atopic diseases) induced and made chronic by tissue cells whose proliferation is accelerated by LPA mediated by EDG-2.
Claims15
1-6. (canceled)
A method for the treatment and/or prevention of a chronic disease, which comprises administering to a mammal an effective amount of an EDG-2 antagonist.
(canceled)
A remedy and/or preventive of a chronic disease, comprising an EDG-2 antagonist in combination with one or more selected from LPA receptor antagonist, anti-androgenergic agent, α1 receptor blocker or 5α-reductase inhibitor.
Dependencies are inferred from the claim text.