Anti-obesity compositions
AssigneeHoffmann-La Roche Inc.
InventorsJacques Bailly, Rainer Martin, Susanne Raab
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Abstract
The present invention relates to compositions and methods for treating obesity. More particularly, the invention relates to a composition comprising a lipase inhibitor such as orlistat, and glucomannan such as konjac as well as methods for utilizing such compositions and kits for carrying out this method.
Claims49
A pharmaceutical composition comprising from about 0.1% by weight to about 20% by weight, based upon the weight of the composition, of a lipase inhibitor and from about 10% by weight to about 75% by weight, based upon the weight of the composition, of glucomannan and from about 0.1% to about 90% by weight, based upon the weight of the composition, of one or more pharmaceutically acceptable excipients.
A method of combating obesity in human patients comprising administering to said human patients a lipase inhibitor in an amount effective to combat said obesity, said lipase inhibitor being administered in conjunction with glucomannan, said glucomannan being administered in an amount sufficient to reduce the gastro-intestinal adverse events caused after administration of a lipase inhibitor.
The kit for the treatment of obesity containing as a first component a lipase inhibitor and as a second component glucomannan.
Dependencies are inferred from the claim text.