Loading patent…
OwnerRoss Basch, Simon Karpatkin +1inventors
InventorsRoss Basch, Simon Karpatkin, Rashmi Gupta
Estimating the term…
The present invention relates to pluripotent stem cells and methods of promoting long term growth of such cells. In particular, the methods described are used to enhance the proliferation of hematopoietic stem cells, hematopoietic precursor cells, hemangioblasts and endothelial stem cells. The present invention also relates to methods of using such cells, comprising introducing such stem cells, into the host. The present invention also relates to pharmaceutical compositions comprising the cells and such compositions may include growth factors or cytokines to allow for further cell growth and/or cellular differentiation. The invention further relates to methods of in vivo administration of a protein or gene of interest comprising transfecting the stem cells grown by the methods described, with a construct comprising DNA which encodes a protein of interest and then introducing the stem cell into the host where the protein or gene of interest is expressed.
A method for culturing, growing and/or maintaining stem cells or derivatives thereof comprising the steps of:
Dependencies are inferred from the claim text.