Cvd assay
AssigneeAxix-Shield ASA
InventorErling Sundrehagen
Life of this patent
Estimating the term…
Abstract
An assay method for the detection of potential for CVD or propensity to CVD in a human or non-human animal subject, said method comprising assessing the concentration of calprotectin in a calprotectin-containing sample taken from said subject.
Claims27
An assay method for the detection of potential for CVD or propensity to CVD in a human or non-human animal subject, said method comprising assessing the concentration of calprotectin in a calprotectin-containing sample taken from said subject.
An assay method for the determination of calprotectin in a calprotectin-containing body fluid, said method comprising the steps of:
- (a) obtaining a calprotectin-containing liquid sample of, or derived from, said fluid;
- (b) contacting said sample of said body fluid with a nanoparticle-bound anti-calprotectin antibody or antibody fragment, to bind said calprotectin;
- and
- (c) assessing the calprotectin content by turbidimetry,
- wherein the diameter of the antibody or antibody fragment coated nanoparticles is in the range 65-140 nm.
An automated apparatus to receive a calprotectin-containing body fluid sample, apply the anti-calprotectin antibody or antibody fragment immobilised on nanoparticles, optionally apply an opacification enhancer, and assess calprotectin content.
Dependencies are inferred from the claim text.