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US 2006/0134677 A1Published application
Methods for drug discovery, disease treatment, and diagnosis using metabolomics
OwnerRima Kaddurah-Daouk, Bruce Kristalinventors
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Abstract
The small molecule profiles of cells are compared to identify small molecules which are modulated in altered states. Cellular small molecule libraries, methods of identifying tissue sources, methods for treating genetic and non-genetic diseases, and methods for predicting the efficacy of drugs are also discussed.
Claims11
A method for identifying small molecules relevant to Huntington's disease, comprising:
- obtaining a small molecule profile of a subject suffering from Huntington's disease;
- and
- comparing the small molecule profile to a standard small molecule profile;
- thereby identifying the small molecules relevant to Huntington's disease.
1 more element
A method for metabolomically monitoring the progression of Huntington's disease in a subject comprising:
- obtaining a small molecule profile of a sample from a subject suffering from Huntington's disease;
- and
- monitoring changes in the small molecule profile of the subject over time, thereby monitoring the progression of the disease.
Dependencies are inferred from the claim text.