Back to results
US 2006/0134616 A1Published application
Sonication to selectively lyse different cell types
AssigneeMicroFluidic Systems, Inc.
InventorsPhillip Belgrader, Bob Yuan
Life of this patent
Estimating the term…
Abstract
A sonication apparatus is directed to a microfluidic-based system to automate differential extraction of specific cell types within a mixed sample. The microfluidic-based system includes a sonication module for selective cell lysis, separating means to eliminate centrifugation, high surface area pillar chip modules to purify DNA from a cell lysate, and microfluidic circuitry to integrate the steps in an automated platform.
Claims22
1-38. (canceled)
An apparatus to selectively lyse a specific type of cell, the apparatus comprising:
- a. a sonication chamber to receive a sample and to provide a first sonication energy, the sample having at least two different cell types, wherein a first cell type is lysed at the first sonication energy to form a first lysate;
- b. separating means to separate the first lysate from the sample;
- c. a collection vessel to collect the first lysate;
- and
- d. microfluidic circuitry to couple the sonication chamber, the separating means, and the collection vessel.
2 more elements
Dependencies are inferred from the claim text.