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OwnerPeter Palese, Adolfo Garcia-Sastre +1inventors
InventorsPeter Palese, Adolfo Garcia-Sastre, Christopher Basler
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A novel virus, the Chris-like virus, has been identified and characterised. Sequences derived from a new paramyxovirus, Chris-like virus (CV), are provided. These sequences encode viral proteins with similarity to recognized viral proteins in other known and characterized paramyxoviruses. The CV viral sequences and the polypeptides encoded therein are useful for the detection, immunological protection and therapy of CV. The sequences provided by the invention are also useful for the isolation and characterization of CV, for the propagation of CV or its viral components in cells or tissue culture, for the generation of immunogenic polypeptides and vaccines, and for the screening and identification of antiviral agents for CV.
An isolated paramyxovirus comprising a nucleic acid molecule hybridizing under stringent conditions to SEQ ID NOS:
An isolated paramyxovirus comprising polypeptides having at least 90% identity to SEQ ID NOS:
An isolated paramyxovirus comprising an identifying characteristic selected from the group consisting of:
An isolated nucleic acid molecule comprising (a) a nucleic acid sequence hybridizing under stringent conditions to a nucleic acid sequence SEQ ID NOS:
An isolated nucleic acid molecule comprising SEQ ID NOS:
An isolated nucleic acid molecule comprising a nucleic acid sequence encoding a polypeptide comprising SEQ ID NOS:
A method for producing a polypeptide comprising SEQ ID NOS:
An isolated polypeptide comprising a polypeptide sequence having at least 90% identity to SEQ ID NOS:
A nucleic acid molecule comprising a chris-like virus nucleic acid sequence operably linked to a heterologous nucleic acid sequence encoding a heterologous protein.
Dependencies are inferred from the claim text.