Synergistic composition for the treatment of diabetes mellitus
AssigneeIndus Biotech Pvt. Ltd.
InventorsSunil Bhaskaran, Vishwaraman Mohan
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Abstract
The present invention relates to a synergistic composition for the treatment of diabetes in a subject in need thereof, said composition—comprising Trigonelline of concentration ranging between 20 to 30%, amino acids of concentration ranging between 20 to 60%, and soluble fiber of concentration ranging between 10 to 60%, optionally along with pharmaceutically acceptable additives, a process thereof and also, a method of treating diabetes.
Claims8
A process for the preparation of a synergistic composition from plant fenugreek comprising Trigonelline of concentration ranging between 20 to 30%, amino acids of concentration ranging between 20 to 60%, and soluble fiber of concentration ranging between 10 to 60%, optionally along with pharmaceutically acceptable additives, said process consisting steps of:
- a. flaking fenugreek seeds,
- b. extracting the flaked seeds with hydro-alcohol,
- c. concentrating the extract under vacuum to remove alcohol,
- d. extracting the concentrate with n-hexane to remove fats and lipids,
- e. diluting the defatted concentrated,
- f. filtration of the diluted extract to remove insolubles to obtain resultant,
- g. filtering the resultant through column chromatography to elute amino-acids, and Trigonelline, and
- h. adding fiber of fenugreek into the amino acids and Trigonelline to obtain the synergistic composition.
Dependencies are inferred from the claim text.