Pharmaceutical composition based on agonist of benzodiazepine
AssigneeSigma Pharma Ltda.
InventorsGuido Vandoni, Carlo Oliani, Adriano Coelho, Heny Zaniboni
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Abstract
The present invention describes the use of pharmaceutical compounds in pharmaceutical compositions for sublingual administration, including as active ingredient thereof, an agonist of the central receptor of benzodiazepinics chosen among diazepam, lorazepam, bromazepam, triazolam, alprazolam, flunitrazepam, nitrazepam and midazolam maleate, in a mixture with a pharmaceutical excipient consisting of, at least, 70% of the weight of the final formulation containing 40-45% by weight of lactose, 15-27% by weight of sorbitol and 12-16% by weight of cellulose.
Claims7
A pharmaceutical composition comprising an agonist of the central receptor of benzodiazepinics, formulated for sublingual administration, comprising as one of its active ingredient, an agonist of the central receptor of benzodiazepinics selected from the group consisting of diazepam, lorazepam, bromazepam, triazolam, alprazolam, flunitrazepam, nitrazepam and midazolam maleate, in a mixture with excipients comprising at least 70% of the weight of the final formulation, and comprising 40-45% by weight of lactose, 15-27% by weight of sorbitol and 12-16% by weight of cellulose.
Dependencies are inferred from the claim text.