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US 2006/0134162 A1Published application
Methods for fabricating a drug delivery device
OwnerChristopher Larsoninventor
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Abstract
A drug delivery device for placement in the eye includes a drug core comprising a pharmaceutically active agent, and a holder that holds the drug core. The holder is made of a material impermeable to passage of the active agent and includes an opening for passage of the pharmaceutically agent therethrough to eye tissue. The device includes a layer of material permeable to passage of the active agent. This invention provides improved methods that do not require the use of adhesives to form the drug delivery device.
Claims26
A method of forming a drug delivery device comprising:
- providing a drug holder having at least one surface to be bonded,
- providing a base having at least one surface to be bonded,
- exposing the surfaces to be bonded to reactive conditions suitable to form reactive groups selected from the group consisting of silanol, hydroxyl, and carboxylic acid groups groups, and
- contacting the surfaces to be bonded having the reactive groups with each other under conditions suitable to allow reaction of the reactive groups to occur to form a covalently bonded drug delivery device.
1 more element
Dependencies are inferred from the claim text.