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US 2006/0134129 A1Published application
Synthetic HLA binding peptide analogues and uses thereof
OwnerDavid Scheinberg, Javier Pinilla-Ibarzinventors
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Abstract
The present invention is directed to immunogenic bcr-abl-based peptides, compositions and vaccines comprising same, and methods of use thereof for treating, inhibiting or reducing the incidence of a bcr-abl-expressing cancer, and methods of generating a heteroclitic immune response against, or cytotoxic T cells specifically recognizing bcr-abl-expressing cancer cells.
Claims26
A bcr-abl-based peptide, comprising a sequence of amino acids that is an analogue peptide of a native bcr-abl breakpoint peptide that specifically binds to a HLA A0201 or HLA A0301 molecule on a cell surface,
Dependencies are inferred from the claim text.