Composition and method for improving function of embryonic kidney transplants
AssigneeWashington University
InventorsMarc Hammerman, Sharon Rogers
Life of this patent
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Abstract
Methods and compositions are disclosed for use with embryonic metanephric tissue so as to increase the functioning renal mass obtained upon transplantation into a recipient.
Claims29
Isolated embryonic metanephric tissue that has been treated with a growth factor composition comprising at least one growth factor for metanephric development, wherein said treated metanephric tissue has enhanced renal development or function in a recipient as compared to metanephric tissue which has not been treated with said growth factor composition.
Isolated porcine embryonic metanephric tissue.
A composition comprising embryonic metanephric tissue and a growth factor composition.
A method comprising contacting isolated embryonic metanephric tissue with a growth factor composition comprising at least one growth factor for metanephric growth.
A chimeric kidney comprising tissue derived from embryonic metanephric tissue.
Dependencies are inferred from the claim text.