Oral compositions for prevention and reduction of bacterial adhesion to oral surfaces
AssigneeColgate-Palmolive Company
InventorsHarsh Trivedi, Tao Xu, Kimberlee Panaligan
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Abstract
The present invention encompasses an oral composition containing an anti-adhesion agent, preferably a cysteine protease and most preferably ficin. In another aspect, the cysteine protease is in combination with one or more ingredients, such as antibacterial agent and surfactant. The anti-adhesion agent mitigates interaction between a subject oral cavity and plaque-forming materials.
Claims17
An oral composition comprising an anti-adhesion agent comprising ficin, the anti-adhesion agent present in an amount effective to mitigate interaction between a subject oral cavity and plaque-forming material.
An oral composition comprising an anti-adhesion agent in an amount by weight of at least 0.01 parts per 100 parts of the composition, wherein the anti-adhesion agent comprises a cysteine protease having a milk-clotting activity greater than papain.
A method of reducing growth of plaque in an oral cavity of a subject comprising contacting the oral cavity with an effective amount of an anti-adhesion protease enzyme, thereby mitigating interaction between the subject oral cavity and plaque-forming material.
An oral composition comprising an anti-adhesion agent comprising ficin and an antibacterial agent.
An oral composition having at least one antibacterial agent that includes cetyl pyridinium and at least one anti-adhesion protease enzyme that has a milk-clotting activity greater than papain.
Dependencies are inferred from the claim text.