Oral and dental composition
OwnerPatrick Shanahaninventor
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Abstract
The invention provides an oral and dental composition comprising an effective antibacterial amount of a combination of a physiologically acceptable divalent metal ion; a quaternary ammonium compound; chitosan or a chitosan derivative in a form to facilitate interaction with the other two components of the combination; and a physiologically acceptable excipient.
Claims73
An oral and dental composition comprising an effective antibacterial amount of a combination of:
- a) a physiologically acceptable divalent metal ion;
- b) a quaternary ammonium compound;
- and
- c) chitosan or a chitosan derivative in a form to facilitate interaction with the other two components of the combination;
- and a physiologically acceptable excipient.
An oral and dental composition comprising an effective antibacterial amount of a combination of:
- a) a physiologically acceptable divalent ion selected from the group consisting of Zn2+, Cu2+ and Sn2+;
- b) cetyl pryridinium chloride;
- and
- c) chitosan or a chitosan derivative in a form to facilitate interaction with the other two components of the combination;
- and a physiologically acceptable excipient.
An oral and dental composition for the treatment of xerostomia comprising an effective antibacterial amount of a combination of:
- a) a physiologically acceptable divalent metal ion;
- b) a quaternary ammonium compound;
- and
- c) chitosan or a chitosan derivative in a form to facilitate interaction with the other two components of the combination;
- and a physiologically acceptable excipient.
A method of inhibiting or preventing an oral or dental condition in a subject, the method comprising contacting an oral cavity and/or teeth of the subject with a composition comprising an effective antibacterial amount of a combination of:
- a) a physiologically acceptable divalent metal ion;
- b) a quaternary ammonium compound;
- and
- c) chitosan or a chitosan derivative in a form to facilitate interaction with the other two components of the combination;
- and a physiologically acceptable excipient, for a time and under conditions sufficient to inhibit or prevent the condition.
A method of inhibiting or preventing xerostomia in a subject, the method comprising contacting an oral cavity and/or teeth of the subject with a composition comprising an effective antibacterial amount of a combination of:
- a) a physiologically acceptable divalent metal ion;
- b) a quaternary ammonium compound;
- and
- c) chitosan or a chitosan derivative in a form to facilitate interaction with the other two components of the combination;
- and a physiologically acceptable excipient, for a time and under conditions sufficient to inhibit or prevent the condition.
An antibacterial oro-dental system comprising a composition including a physiologically acceptable divalent metal ion, a quaternary ammonium compound, chitosan or a chitosan derivative, a physiologically acceptable excipient, and saliva in the oral cavity of a human or animal subject, the chitosan or chitosan derivative present in a form to facilitate interaction with the components of the system including the saliva of the subject.
Dependencies are inferred from the claim text.