Use of buckysome or carbon nanotube for drug delivery
AssigneeC Sixty Inc.
InventorsAndreas Hirsch, Uri Sagman, Stephen Wilson
Life of this patent
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Abstract
Compositions and methods for administering a therapeutic agent to a mammal are disclosed. The compositions comprise either (i) vesicles comprising an amphiphilic substituted fullerene, wherein the therapeutic agent is present in the vesicle interior or between layers of the vesicle wall, (ii) a substituted fullerene, comprising a fullerene core and a functional moiety, wherein the therapeutic agent is associated with the substituted fullerene, or (iii) carbon nanotubes, wherein the therapeutic agent is covalently bonded to the carbon nanotubes.
Claims11
1-34. (canceled)
A substituted fullerene, comprising:
- a fullerene moiety comprising n carbon atoms, wherein n is an integer and 60≦n≦240, and
- a functional group selected from the group consisting of biotin-containing moieties, antigen-binding moieties, and tissue-recognition moieties.
A method of administering a therapeutic agent to a mammal, comprising:
- (i) administering a solution comprising (a) a substituted fullerene comprising (a-i) a fullerene moiety comprising n carbon atoms, wherein n is an integer and 60≦n≦240, and (a-ii) a functional group selected from the group consisting of biotin-containing moieties, antigen-binding moieties, and tissue-recognition moieties, and (b) a pharmaceutically effective amount of the therapeutic agent, wherein the therapeutic agent is associated with the substituted fullerene.
(canceled)
Dependencies are inferred from the claim text.