Method and device for chromatography comprising a concentration step
OwnerMichel Bailly, Roger-Marc Nicoud +2inventors
InventorsMichel Bailly, Roger-Marc Nicoud, Philippe Adam, Olivier Ludemann-Hombourger
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Abstract
The invention concerns a method for multiple-column chromatographic spearation producing at least two fractions, comprsing the following steps: in output of the extract, zone 1, or the raffinate zone, zone III: (i) drawing at least part of the output flow of said zone; (ii) concentrationg said part; and (iii) re-injecting at least partly said concentrated part. The invention also concerns a device for implementing said method.
Claims16
A multi-column chromatography separation process producing at least two fractions, comprising the following steps, at the outlet from the extract zone, zone I, or raffinate zone, zone III:
- (i) at least a part of the outlet flow rate from said zone is drawn off;
- (ii) said part is concentrated;
- and
- (iii) the concentrated part is at least partially reinjected.
Chromatography apparatus comprising:
- i. a plurality of separation columns;
- II. a drawing-off point at the outlet from said columns for drawing off at least a part of the outlet flow rate from a column;
- III. a device for concentration said part;
- IV. a reinjection point immediately after the drawing-off point for reinjecting at least partially the concentrated part.
(canceled)
Dependencies are inferred from the claim text.