The method of dispensing liquid in a pipetting device comprising a housing with a holder to mount a pipette, whereas an air pump connected to the pipette, and a processor controlling the device operation is disposed in the housing, wherein after aspiration by the pump of liquid into the pipette, the required size of the liquid dose is dispensed form the pipette in proportion to the amount of atmospheric air supplied thereto through a valve or a set of valves connected to the pipette, characterized by that the amount of the supplied atmospheric air is programmed in the processor by determination of time and/or flow rate and/or damping of the supply of atmospheric air to the pipette.