Inhibition of atherosclerosis by diindolylmethane analogs

Abstract

Diindolylmethane analogs such as 1,1-bis(3′-indolyl)-1-(p-substituted phenyl)methanes can be used to treat atherosclerosis and other vascular disease states. The analogs have been shown to display antiinflammatory effects in endothelial cells, suggesting their clinical applicability.

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